Wildfire Smoke and Pregnancy: New Study Links Smoke Exposure to Higher Preterm Birth Risk (2025)

The devastating impact of wildfire smoke on preterm births is a growing concern, and a recent study sheds light on this critical issue. The link between wildfire smoke and preterm birth is a wake-up call for us all.

Approximately 10% of American babies are born prematurely, and this statistic is a stark reminder of the potential health risks associated with early birth. From immediate health complications to long-term developmental issues, the impact of preterm birth is far-reaching and underscores the importance of prevention.

Researchers have long suspected a connection between wildfire smoke, a rapidly growing source of air pollution, and preterm birth. However, previous studies lacked the scale and scope to draw definitive conclusions. That's where a new study led by the University of Washington steps in, analyzing data from over 20,000 births and providing crucial insights.

The study, published in The Lancet Planetary Health, utilized data from the Environmental influences on Child Health Outcomes (ECHO) program, a federal research project focused on environmental factors and their impact on children's health. The sample included births across the contiguous United States from 2006 to 2020.

Researchers estimated participants' exposure to fine particulate matter (PM2.5) generated by wildfire smoke, considering both the average daily exposure and the total number of exposure days. They also assessed the intensity of smoke exposure by evaluating how frequently participants were exposed to wildfire PM2.5 levels above specific thresholds.

The findings were clear: pregnant individuals exposed to more intense wildfire smoke were at a higher risk of preterm birth. In mid-pregnancy, any exposure to smoke was associated with an increased risk, with the highest risk observed around the 21st week of gestation. In late pregnancy, the risk was most pronounced when exposed to high concentrations of wildfire PM2.5, exceeding 10 micrograms per cubic meter.

"The second trimester is a critical period for placental growth and development," explained co-author Dr. Catherine Karr, a UW professor of environmental and occupational health sciences and pediatrics. "Wildfire smoke particles may interfere with placental health, and some can even enter the bloodstream and reach the placenta or fetus."

The link between wildfire smoke and preterm birth was most pronounced in the Western United States, where individuals experienced the highest concentrations of wildfire PM2.5 and the greatest number of high-intensity smoke days. This suggests that the intensity and duration of exposure play a significant role.

But why the regional differences? The composition of wildfire smoke varies across the country. In the West, smoke often originates from nearby fires, while in regions like the Midwest, it tends to drift in from distant blazes. The toxicity of smoke evolves as it ages and interacts with sunlight and airborne chemicals, potentially influencing the results. External factors like heat and housing quality may also contribute to the observed variations.

While further research is needed to understand the precise mechanisms, the evidence is compelling enough to take action. "There are opportunities to empower pregnant individuals with tools to protect themselves during smoke events," said lead author Allison Sherris, a UW postdoctoral researcher. "Public health messaging about wildfire smoke should also highlight pregnant individuals as a vulnerable group."

This research was funded by the Environmental influences on Child Health Outcomes (ECHO) program at the National Institutes of Health. The full list of funding awards and co-authors is available with the paper.

Wildfire Smoke and Pregnancy: New Study Links Smoke Exposure to Higher Preterm Birth Risk (2025)

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